(1) 2011-08 至 2018-04，东南大学，生物医学工程，博士（生物信息学方向）， 导师：陆祖宏

(2) 2007-08 至 2011-06，东南大学，生物医学工程，学士

(1) 2020-05 至 现在，北京交通大学，理学院/物理科学与工程学院，讲师

(2) 2018-12 至 2020-02，美国杜克大学医学院（Duke University School of Medicine），生物统计与生物信息系，博士后

(3) 2012-07 至 2014-07，美国贝勒医学院（Baylor College of Medicine），博士前研究员

• 生物信息学

• 生物学硕士

本科生教学：主讲《组学信息学》、《生命科学纵横》、《个体化医学——医学发展新趋势》；参与《理学之美（上）》、《理学之美（下）》

硕士生培养：

1. 李欣怡 2022年9月入学

2. 陈代川 2023年9月入学

3. 王恩凯 2024年9月入学

其他学生培养：

纳米2201班主任、物研2303班主任

• Xu H, Kang Y, Liang T, Lu S, Xia X, Lu Z, Hu L, Guo L, Zhang L, Huang J, Ye L, Jiang P, Liu Y, Li X, Zhai J, Wang Zi, Liu Y. SNP-based and haplotype-based genome-wide association on drug dependence in Han Chinese. BMC Genomics. 2024, 25(1):255. (2023 IF=4.4, 中科院2区TOP)
  
• Xu H, Gao H, Wang C, Cheng X, Li Z, Lei C, Huang X, Li W, Yue Z, Tian S, Zhao X, Xue T, Xing T, Li J, Wang Y, Duan Y, Wang T, Zhang R. Optical Genome Mapping Reveals Novel Structural Variants in Lymphoblastic Lymphoma. Journal of Pediatric Hematology/Oncology. 2024, 46(1):p e71-e82.
• Xu H, Lin S, Zhou Z, Li D, Zhang X, Yu M, Zhao R, Wang Y, Qian J, Li X, Li B, Wei C, Chen K, Yoshimura T, Wang J, Huang J. New genetic and epigenetic insights into the chemokine system: the latest discoveries aiding progression toward precision medicine. Cellular & Molecular Immunology. 2023, 20(7):739-776. (2023 IF=24.1, 中科院1区TOP)
• Gao H, Xu H, Wang C, Cui L, Huang X, Li W, Yue Z, Tian S, Zhao X, Xue T, Xing T, Li J, Wang Y, Zhang R, Li Z, Wang T. Optical Genome Mapping for Comprehensive Assessment of Chromosomal Aberrations and Discovery of New Fusion Genes in Pediatric B-Acute Lymphoblastic Leukemia. Cancers. 2023; 15(1):35. (2023 IF=5.2, 共一) (与北京儿童医院合作, 负责生信贡献)
• Hua J, Xu H, Zhang Y, Ge J, Liu M, Wang Y, Wei Y, Shi Y, Hou L, Jiang H. Enhancement of recombinant human IL-24 (rhIL-24) protein production from site-specific integrated engineered CHO cells by sodium butyrate treatment. Bioprocess Biosystem Engineering, 2022, 45(12):1979-1991. (2022 IF=3.434, 共一)
• Lin S, Xu H, Pang M, Zhou X, Pan Y, Zhang L, Guan X, Wang X, Lin B, Tian R, Chen K, Zhang X, Yang Z, Ji F, Huang Y, Wei W, Gong W, Ren J, Wang JM, Guo M and Huang J. CpG Site-Specific Methylation-Modulated Divergent Expression of PRSS3 Transcript Variants Facilitates Nongenetic Intratumor Heterogeneity in Human Hepatocellular Carcinoma. Frontiers in Oncology, 2022, 12:831268. (2022 IF=5.738, 共一)  (与北京胸科医院合作, 负责生信贡献)
• Dang M, Xu H, Zhang J, Wang W, Bai L, Fang N, Liang L, Zhang J, Liu F, Wu Q, Wang S, Guan Y. Inferring fetal fractions from read heterozygosity empowers the noninvasive prenatal screening. Genetics in Medicine, 2020, 22(2):301-8. (2020 IF=8.683，中科院1区TOP，共一)
• Xu H, Wang S, Ma L, Huang S, Liang L, Liu Q, Liu Y, Liu K, Tan Z, Ban H, Guan Y, Lu Z. Informative priors on fetal fraction increase power of the noninvasive prenatal screen. Genetics in Medicine, 2018, 20(8):817-24. (2018 IF=9.937, 中科院1区TOP)
• Xu H, Guan Y. Detecting Local Haplotype Sharing and Haplotype Association. Genetics, 2014, 197(3):823-38. (2014 IF=4.866)(被引用=33)

• Cheng Y, Dong L, Bu D, Han L, Zhao Y, Liu J, Guo X, Xu H, Yu J. Optical Genome Mapping Reveals the Landscape of Structural Variations and their Clinical Significance in HBOC-related Breast Cancer. Frontiers in Bioscience Landmark. 2024, 29(1), 2. (2023 IF=3.1, 共同通讯) (与天津肿瘤医院合作, 负责生信贡献)
• Li X, Huang J, Kang Y, Cheng X, Yan Q, Zhang L, Fan J, Xu H. Cancer Stem Cell Biomarkers in the Nervous System. Frontiers in Bioscience Landmark. 2023, 28(12), 362. (2023 IF=3.1)

• Gong S, Pan P, Meng X, Zhang Y, Xu H, Hu H, Cheng X, Yan Q. Integrated Physiologic and Proteomic Analyses Reveal the Molecular Mechanism of Navicula sp. in Response to Ultraviolet Irradiation Stress. International Journal of Molecular Sciences, 2024, 25, 2747.
  
• Sun Y, Liu X, Li W, Wang X, Zhong X, Gao Y, Xu H, Hu H, Zhang L, Cheng X, Yan Q. The regulatory metabolic networks of the Brassica campestris L. hairy roots in response to cadmium stress revealed from proteome studies combined with a transcriptome analysis. Ecotoxicology and Environmental Safety, 2023, 263:115214.(2023 IF=6.8，中科院毒理学1区TOP)
• Lin S, Xu H, Qin L, Pang M, Wang Z, Gu M, Zhang L, Zhao C, Hao X, Zhang Z, Ding W, Ren J, Huang J. UHRF1/DNMT1-MZF1 axis-modulated intragenic site-specific CpGI methylation confers divergent expression and opposing functions of PRSS3 isoforms in lung cancer, Acta Pharmaceutica Sinica B, 2023, 13(5):2086-2106. (2023 IF=14.5, 中科院1区TOP) (与北京胸科医院合作，二作负责生信贡献)
• Zhang J, Fan L, Xu H, Fu Y, Peng X, Zheng Y, Yu, J. He, J. Evolutionary Pattern Comparisons of the SARS-CoV-2 Delta Variant in Countries/Regions with High and Low Vaccine Coverage. Viruses, 2022, 14:2296.
• Hua J, Wei Y, Zhang Y, Xu H, Ge J, Liu M, Wang Y, Shi Y, Hou L, Jiang H. Adaptation process of engineered cell line FCHO/IL-24 stably secreted rhIL-24 in serum-free suspension culture. Protein Expression and Purification, 2022,106154.
• Tian B, Yao J, Lin X, Lv W, Jiang L, Wang Z, Shen J, Xiao H, Xu H, Xu L, Cheng X, Shen H, Qiu C, Luo Z, Zhao L, Yan Q, Deng H-W and Zhang L. Metagenomic study of the gut microbiota associated with cow milk consumption in Chinese peri-/postmenopausal women. Frontiers In Microbiology, 2022, 13:957885. 
• Cheng X, Luo Y, Gao Y, Li S, Xu C, Tang S, Yang Y, Zhang Z, Jiang H, Xu H, Shi S, Yan Q. Surfactant-assisted alkaline pretreatment and enzymatic hydrolysis of Miscanthus sinensis for enhancing sugar recovery with a reduced enzyme loading. Frontiers in Bioengineering and Biotechnology, 2022, 10:918126. 
• Yan X, Xu H, Li Y, Su H, Zhang B, Jia Z. Clustering HIV infections among MSM fuelled by drug and internet. Sexually Transmitted Infections, 2022, 98(2):153.
• Dong W, Tao J, Xia X, Ye L, Xu H, Jiang P, Liu Y. Public Emotions and Rumors Spread During the COVID-19 Epidemic in China: Web-Based Correlation Study. Journal of Medical Internet Research, 2020, 22(11), e21933.
• Yu J, Zhang L, Fu Y, Ji F, Xu H, Huang J, Peng X, Zheng Y, Zhang Y, He J. Analysis of Continuous Mutation and Evolution on Circulating SARS-CoV-2. Evolutionary Bioinformatics, 2020, 16:1-6.

已授权专利：

(1)徐寒黎; 王伟伟; 张静波; 刘珂弟; 刘倩; 唐宇; 数据处理装置, 2021-5-25, 中国, ZL201711499257.6. 

(2)徐寒黎; 王伟伟; 张静波; 刘珂弟; 刘倩; 唐宇; 数据处理方法、装置、存储介质及处理器, 2021-1-5, 中国, ZL201711484713.X. 

(3)徐寒黎; 张静波; 方楠; 王建伟; 伍启熹; 刘倩; 刘珂弟; 唐宇; 基于ctDNA的基因检测装置、存储介质及计算机系统, 2020-6-26, 中国, ZL201811565001.5. 

(4)关永涛; 党明浩; 徐寒黎; 张静波; 方楠; 白灵; 王建伟; 刘倩; 唐宇; 胎儿游离DNA浓度获取方法和装置, 2019-12-17, 中国, ZL201811162012.9.  

(5)王少为; 徐寒黎; 王伟伟; 张静波; 刘斐然; 刘倩; 刘珂弟; 唐宇; 一种非整倍性生物信息的分析方法和分析系统, 2018-7-13, 中国, ZL201710310451.9.   

(6)周晔; 刘倩; 唐宇; 徐寒黎; 李伟伟; 郭现超; 李箐; 测序接头、其制备方法及其在超低频变异检测中的应用, 2018-3-30, 中国, ZL201610342219.9. 

申请中的专利：

(1)徐寒黎; 谢玉婷; 成喜雨; 吕兴; 金怡宸; 马腾跃; 李欣怡. 基于低深度测序数据检测基因组纯合区域的方法及系统.

(2)徐寒黎; 李欣怡; 成喜雨. 一种染色体纯合区域的检测方法、系统及电子设备.

(3)成喜雨; 张泽华; 徐寒黎; 晏琼; 吕兴; 张丽姝; 胡红刚; 李欣怡. 一种宏基因组数据分析系统.

2023-2024学年北京交通大学优秀本科班主任，1/1

2023年度北京交通大学优秀工会干部，1/1

2022年度物理科学与工程学院青年教师教学基本功比赛三等奖，1/1

2021年度北京交通大学优秀工会工作者，1/1

2015年度石景山区科学技术三等奖，2/5