CN EN

JIANG Hong

Professional title:Associate Professor

Office No.:010-51688577-805

Email:jhong@bjtu.edu.cn

Education

1998-2001, Department of Biological Chemistry and Molecular Biology, the Forth Military Medical University, Xi’an, Shaanxi Province, MD

1989-1992, Department of Biology Science, Southwest Normal University, Master

1985-1989, Department of Biology Science, Shaanxi Normal University, Bachelor

Research Field

Cancer Biology

Projects

  1. Preparation and identification of engineering cell line with high expression level of secreted recombinant human IL-24, National Natural Science Foundation of China (No.81071855, 2011)
  2. Preparation and identification of engineering cell line with high expression level of secreted recombinant human IL-24, the Person Project of Beijing Jiaotong University (No. KSRC11004536, 2010)
  3. Key technologies of preparation and optimization of humanized engineering antibody, National Science and Technology Major Project (2009ZX09503-010,2009-2010)
  4. Preparation of tissue engineered uterine slice and its role in Embryonic development, Military Medical Science Foundation (No. 06MA318, 2006-2010)
  5. Study on the role of inhibition apobec-1 gene expression of NF1 by interfering RNA, National Natural Science Foundation of China (No.30200073, 2003-2005)

Teaching Courses

Experiments of Molecular Biology II, for graduate students, M508066B, 2010-2021

Experiments of Molecular Biology I, for undergraduate students, 70S356Q, 2013-2021

Experiments of Biochemistry, for undergraduate students, 70S215Q, 2015-2017

Biology in Kitchen, for undergraduate students, A108012B, 2019-2021

Synopsis of Cancer, for undergraduate students, A108007B, 2015-2021

Biology in Life, for undergraduate students, A108009B, 2014-2021

Essential Biology, for undergraduate students, 70L556Q, 2011-2014

Paper

  1. Yuqi Wang*, Zubiao Niu*, Lulin Zhou*, Yongan Zhou*, Qunfeng Ma*, Yichao Zhu, Mengzhe Liu, Yinan Shi, Yanhong Tai, Qiuju Shao, Jianlin Ge, Jilei Hua, Lihua Gao, Hongyan Huang#, Hong Jiang# and Qiang Sun#. Subtype-Based Analysis of Cell-in-cell Structures in Esophageal Squamous Cell Carcinoma. Front Oncol. 202, 11: 670051. (Corresponding author)
  2. Yao Zhang*, Qunfeng Ma*, Junfeng Wang*, Jianlin Ge, Jill Hua, Yinanshi, Chi Zhang, Mengzhe Liu, Yuqi Wang, Zhinan Chen, Ziling Wang, Yongdong Liu#, Hong Jiang#. Expression, purification, and polyethylene glycol site-specific modification of recombinant human interleukin 24 in Escherichia coli. Protein J. 2019, 38(5): 576-585. (Corresponding author)
  3. Shi YN*, Ma QF*, Yuan Y*, Ma XD, Kong LW, Liu YQ, Cui HJ, Zhang C, Wang M, Li X, Wang JF, Ge JN, Chen ZN, Wang ZL, Jiang H#. IL-24 concentrations not related with age, but affect pro- and anti-inflammatory cytokines differently in healthy donors. Clinical Laboratory. 2017, 63: 1379-1391 (Corresponding author)
  4. Zhang C*, Ma QF*, Shi YN, Li X, Wang M, Wang JF, Ge JL, Chen ZN, WANG ZL and Jiang H# A novel 5-fluorouracil-resistant human esophageal squamous cell carcinoma cell line Eca-109/5-FU with significant drug-resistance-related characteristics. Oncology Reports. 2017; 37: 2942-2954 (Corresponding author)
  5. Ma Q*, Jin B*, Zhang Y*, Shi Y, Zhang C, Luo D, Wang P, Duan C, Song H, Li X, Deng X, Chen Z, Wang Z, Jiang H#, Liu Y#.Secreted recombinant human IL-24 protein inhibits the proliferation of esophageal squamous cell carcinoma Eca-109 cells in vitro and in vivo. Oncology Reports. 2016, 35: 2681-2690 (Corresponding author)
  6. Ma Q*, Deng X*, Jin B, Zhang Y, Luo D, Song H, Wang P, Zhang C, Li X, Shi Y, Liu Y, Chen Z, Wang Z#, Jiang H#. A novel human interleukin-24 peptide created by computer-guided design contributes to suppression of proliferation in esophageal squamous cell carcinoma Eca-109 cells. Oncology Reports. 2015, 33: 193-200 (Corresponding author)
  7. Hong Jiang, XueFeng Deng, Cuimi Duan, Cheng Chen, JunLin Xiang, YingLin Lu, QunFeng Ma#. Somatostatin receptors SSTR2 and SSTR5 are expressed in the human thoracic duct. Lymphology. 2011, 44(1): 21-28
  8. Zhang Yao, Ma QunFeng, Zhang Chi, Shi YiNan, JiangHong. Progress in interleukin 24 gene engineering protein. Mil Med Sci. 2015, 39(10): 797-801. (Corresponding author) (In Chinese)
  9. Hong Jiang, Xiao Feng Zheng, Ying Luo, Jie Zhu, HanJiang Fu, QiangLing Sun, ChangHao Chen, ZhiXian Sun. Cloning and expression of hTRF1 in E coli and preparation of polyclonal antibody. Chinese J Biotechnology. 2004, 20(1): 30-33
  10. Hong Jiang, Xiao Feng Zheng, Ying Luo, Jie Zhu, HanJiang Fu, ZhiXian Sun. Preparation of Ni2+ affinity gel and purification of His6-tag recombinant proteins Bull Acad Mil Med Sci. 2003, 27(1): 47-48 (In Chinese)
  11. Hong Jiang, Ying Luo, Xiao Feng Zheng, ZhiXian Sun. Progress on Tankyrase. Prog Biochen Biophys. 2002, 29(3): 355-358 (In Chinese)
  12. Hong Jiang, XiaoJun Yan, ChengZhi Su, FengChan Han, YongQiang Feng, Yu Hou. Construction and expression of the prokaryotic expression vestor of Hp vacA gene related segment with vacuolating activity. J Cell Mol Immunol. 2001, 17(3): 237-240 (In Chinese)
  13. HanJiang Fu, Jie Zhu, Ming Yang, Zhuoyuan Zhang, Yi Tie, Hong Jiang, ZhiXian Sun, XiaoFei Zheng. A novel method to monitor the expression of microRNAs. Molecular Biotechnology. 2006, 32(3): 197-204 
  14. Jinglan Wang, Yangjun Zhang, Hong Jiang, Yun Cai and Xiaohong Qian. Phosphopeptide detection using automated online IMAC-capillary LC-ESI- MS/MS. Proteomics. 2006, 6(2): 404- 411
  15. Ma QunFeng, JiangHong, LiuKun, ZhuJie, Zheng XiaoFei. Preparation and identification of polyclonal antibody against human IL-24. Chin J Cell Mol Immunol. 2006, 22(3): 380-381. (In Chinese)
  16. Ma QunFeng, JiangHong, LiuKun, ZhuJie, Zheng XiaoFei. Localization of overexpressed MDA- 7/IL - 24 protein. Modern Oncology. 2006, 114(12): 135-137. (In Chinese)
  17. Ma QunFeng, JiangHong, LiuKun, ZhuJie, Zheng XiaoFei. Inhibition of mda-7/ IL-24 recombinant adenovirus on proliferation of small cell lung cancer NCI -H446 cells. Med J Chin PLA. 2006, 31(7): 679-682. (In Chinese)
  18. Hanjiang Fu, Yi Tie, Chengwang Xu, Zhuoyuan Zhang, Jie Zhu, Yingxu Shi, Hong Jiang, Zhixian Sun, Xiaofei Zheng. Identification of human fetal liver miRNAs by a novel method. FEBS Letters. 2005, 579: 3849–3854
  19. Ma QunFeng, JiangHong, LiuKun, ZhuJie, Zheng XiaoFei. Inhibition of human mda-7/ IL-24 gene on the proliferation of human lung cancer cells. J Medical Postgraduates. 2005, 18(9): 779-782. (In Chinese)
  20. Ma QunFeng, JiangHong, LiuKun, ZhuJie, Zheng XiaoFei. Cloning of human interleukin 24 (mda7/ IL-24) gene and its fusion protein expression in E. coli. Bull Acad Mil Med Sci. 2004, 28(3): 221-224. (In Chinese)

Monograph

Jiang Hong, Zheng XiaoFei, Ma QunFeng, Jin BangMing, Cao Yu, Wang LiNa, Chen XiaoLin. The human IL-24 peptide with anti-tumor activity. Chinese patent (ZL201210102549.2).

Jiang Hong, Zheng XiaoFei, Ma QunFeng, Wang Junfeng, Zhang Chi, Shi YiNan, Ge JianLin, Hua JiLei. A method to modify rhIL-24 with PEG. Chinese patent (ZL201710414629.4).