CN EN

HU Honggang

Professional title:Associate Professor

Office No.:010-51688577

Email:hghu@bjtu.edu.cn

Education

Doctor's degree (Ph. D.):        Molecular Genetics, University of Konstanz, Germany, April 2005

Diplom (Master's Degree):     Biology, University of Konstanz, Germany, Aug. 2001

Bachelor's degree:                  Applied Chemistry, Peking University, China, July 1989

Professional Experience

Since 2006, I have been working at Beijing Jiaotong University in the field of biology as a teacher, and carrying out scientific research and teaching work.

Research Field

Tumor cell biology

Synthetic biology

Projects

I have presided over and participated in more than 30 scientific research projects, and now presides over and participates in 5 scientific research projects.

Teaching Courses

Cell Biology, Aspect in life sciences, Organic Chemistry.

Paper

Qian, Z., Yang J., Liu H.H., Yin Y., Hou L.L., and Hu H.G.*, The miR-1204 regulates apoptosis in NSCLC cells by targeting DEK. Folia Histochemica Et Cytobiologica, 2019. 57(2): p. 64-73.

Zhou, Q.C., Deng, X.F., Yang, J., Jiang, H., Qiao, M.X., Liu, H.H., Qian, Z., Hou, L.L., and Hu, H.G.*, Oncogene DEK is highly expressed in lung cancerous tissues and positively regulates cell proliferation as well as invasion. Oncology Letters, 2018. 15(6): p. 8573-8581.

Qiao, M.X., Li, C., Zhang, A.Q., Hou, L.L., Yang, J., and Hu, H.G.*, Regulation of DEK expression by AP-2 alpha and methylation level of DEK promoter in hepatocellular carcinoma. Oncology Reports, 2016. 36(4): p. 2382-2390.

Zhou, Q.C., Hu, H.G.*, and Hou, L.L., Discover, Develop & Validate - Advance and Prospect of Tumor Biomarkers. Clinical Laboratory, 2015. 61(11): p. 1589-1599.

Li, C., Hu, H.G.*, and Hou, L.L., Ethical Controversy in Embryonic Stem Cell Research and Discussions on Public Policies. Proceedings of the 2013 International Academic Workshop on Social Science (Iaw-Sc 2013), 2013. 50: p. 950-954.

Zhang L.S., Hu H.G., Liu Y.J., Li J., Yu P., Zhang F., Yang T.L., Tian Q., Zheng Y.P., Guo Y., and Deng H.W., A follow-up association study of two genetic variants for bone mineral density variation in Caucasians. Osteoporos Int, 2012. 23(7): 1867-75.

Sun W.M., Dai X.X., Zheng Y.P., Wang J.W., Hou L.L., Du J., and Hu H.G.*, On-column refolding purification of DT389-hIL13 recombinant protein expressed in Escherichia coli. Protein Expression and Purification, 2011. 75(1): 83-88.

Hua Y., Hu H.G.*, Peng X.L., Progress in studies on the DEK protein and its involvement in cellular apoptosis. Sci China Ser C-Life Sci, 2009, 52(7): 637-642

Hu H.G., Baack M., and Knippers R., Proteins of the origin recognition complex (ORC) and DNA topoisomerases on mammalian chromatin. BMC Mol Biol, 2009, 10: 36

Hu H.G., Scholten I., Gruss C., and Knippers R., The distribution of the DEK protein in mammalian chromatin. Biochem Biophys Res Commun, 2007, 358: 1008-14.

Hu H.G., Illges H., Gruss C., and Knippers R., Distribution of the chromatin protein DEK distinguishes active and inactive CD21/CR2 gene in pre- and mature B lymphocytes. Int Immunol, 2005, 17: 789-96.