虞结梅

博士、副研究员

基本信息

办公电话：010-51684351 电子邮件： jmyu1@bjtu.edu.cn
通讯地址：北京市海淀区上园村3号 邮编：100044

教育背景

 2010.09-2013.07                  中国疾病预防控制中心       博士                                  免疫学


工作经历

2010.09-2010.11    美国华盛顿大学圣路易斯医学医学院          访问学者

2013.07-2014.06    中国疾病预防控制中心病毒病预防控制所   助理研究员

2014.07-2019.11    中国疾病预防控制中心病毒病预防控制所   副研究员

2019.11 - 至今        北京交通大学                                                  副教授

研究方向

  • 生物化学与分子生物学
  • 生物信息学

招生专业

  • 生物学硕士

科研项目

  1. 国家重点研发计划，“新冠等重要呼吸道病原共感染谱及人群免疫特征研究”，任务。（项目编号：2024YFC2309200）。 
  2. 国家自然科学青年基金，“人诺如病毒流行株在免疫抑制病人中的分子进化机制研究”（批准号：81702007）；
  3. 十三五科技部重大专项，“胞内固有免疫网络在病毒性传染病防控中的应用”，子课题。（项目编号：2018ZX10301408）；
  4. 国家自然科学基金重大项目，“热带、高原等特殊地理环境的重要野生动物携带的病原体谱系”，任务。（批准号：81290345）；
  5. 校基本业务人才基金，“病毒基因组结构修饰及其增强RSV活疫苗安全性和有效性的研究”（编号：2020RC016）；
  6. 十一五及十二五传染病重大专项，“未知病原体筛查体系和罕见病原体检测技术”任务。（编号：2009ZX10004-001与2011ZX10004）；
  7. 盖茨基金会国际合作项目，“腹泻与正常儿童粪便标本中新病原的发现”（基金编号：OPP1016839）。


教学工作

1. 《分子病毒学》

2. 《生命科学纵横》

3. 《传染病的防控》

4. 《大学生实用写作》

论文/期刊

以第一作者或通讯作者发表论文如下:

28.Zhao W, Gao ZY, Guo CY, Zhang YY, Zhang Y, Wang QY, Yu JM (通讯作者). A dual typing system establishment and global diversity analysis for sapoviruses. BMC genomics. 2024, 25 (1):1131.

27.Yu JM, Liang ZY, Fu YH, Peng XL, Zheng YP, Dong YJ, He JS. Coexistence of adeno-associated virus 2 with adenovirus 18 or herpesvirus may be associated with severe lingual papillomatosis in an immunocompromised individual. Virologica Sinica. 2024, 39(4): 705-707.

26.虞结梅，郑妍鹏，彭向雷，付远辉，何金生。人呼吸道合胞病毒疫苗研发的突破和挑战。中国食品药品监管。2023, 12：62-71.

25.Guo CY, Zhang Y, Zhang YY, Zhao W, Peng XL, Zheng YP, Fu YH, Yu JM (通讯作者), He JS. Comparative analysis of human respiratory syncytial virus evolutionary patterns during the COVID-19 pandemic and pre-pandemic periods. Frontiers in Microbiology. 2023 December. 4: 1298026.

24.Zheng SY, Zhang YP, Liu YX, Zhao W, Peng XL, Zheng YP, Fu YH, Yu JM (通讯作者), He JS. Tracking of Mutational Signature of SARS-CoV-2 Omicron on Distinct Continents and Little Difference was found. Viruses. 2023 Jan, 15, 321. 

23.Zhang JH, Fan LQ, Xu HL, Peng XL, Fu YH, Zheng YP, Yu JM (通讯作者), He JS. Evolutionary Pattern Comparisons of the SARS-CoV-2 Delta Variant in Countries/Regions with High and Low Vaccine Coverage. Viruses. 2022 Oct 19;14(10):2296.doi: 10.3390/v14102296.

22. Zheng GL, Zhu ZX, Cui JL, Yu JM (通讯作者). Evolutionary analyses of emerging GII.2[P16] and GII.4 Sydney [P16] noroviruses. Virus Evolution. 2022, 8(1), 1–11. 

21. Yu JM. What Is the Potential Cause for the Predominance of GII.2[P16] Norovirus in Acute Gastroenteritis Outbreaks in China? China CDC Weekly. 2022, 4(2): 27-30

20. Fan LQ, Hu XY, Chen YY, Peng XL, Fu YH, Zheng YP, Yu JM (通讯作者), He JS. Biological Significance of the Genomic Variation and Structural Dynamics of SARS-CoV-2 B.1.1617. Frontiers in Microbiology. 2021. Doi: 10.3389/fmicb.2021.750725.

19. Yu JM, Fu YH, Peng XL, Zheng YP, He JS. Genetic diversity and molecular evolution of human respiratory syncytial virus A and B. Scientific Reports. 2021, 11:12941.

18. Yu JM, Wang ZH, Liu N, Zhang Q, Dong YJ, Duan ZJ. Complete genome of a novel recombinant human astrovirus and its quasispecies in patients following hematpoietic stem cell transplantation. Virus research. 2020:198138. 

17. Yu JM, Zhang LS, Fu YH, Ji FM, Xu HL, Huang JQ, Peng XL, Zheng YP, Zhang Y, He JS. Analysis of continuous mutation and evolution on circulating SARS-CoV-2. Evolutionary Bioinformatics. 2020. 

16. Yu JM, Liang ZY, Guo K, Sun XM, Zhang Q, Dong YJ, Duan ZJ. Intra-Host Evolution of Norovirus GII.4 in a Chronic Infected Patient With Hematopoietic Stem Cell Transplantation. Frontiers in Microbiology. 2020, 11:375. 

15. Guo K, Li LL, Zhang Q, Yu JM, Ye Y. Diversified Variants of Astrovirus MLB2 in Patients Following Hematopoietic Stem Cell Transplantation and the Evolutionary Rates and Patterns of the Virus. Evolutionary Bioinformatics. 2019 15:1-6.(第一通讯作者) 

14. Xin YY, Li LL,Ao YY, Xie ZP, Li JS, Duan ZJ,Yu JM & Zhang B. A novel astrovirus identified in wild rhesus monkey feces in China. Archives of Virology. 2019, 164:2385-2388.(通讯作者) 

13. Yu JM, Li LL, Xie GC, Zhang CY, Ao YY, Duan ZJ. Experimental infection of Marmota monax with a novel hepatitis A virus. Archives of Virology. 2018, 163(5):1187-1193. 

12. Ao YY, Li XY, Li LL, Xie XL, Jin D, Yu JM, Lu S, Duan ZJ. Two novel bocaparvovirus species identified in wild Himalayan marmots. Science China Life Sciences.2017 60(12):1348-1356. (通讯作者) 

11. Yu JM, Ao YY, Liu N, Li LL, Duan ZJ. Identification of a novel cosavirus species in feces of children and its relationship with acute gastroenteritis in China. Clinical Microbiology and Infection. 2017, 23(8):550-554. 

10. Yu JM, Li LL, Zhang CY, Lu S, Ao YY, Gao HC, Xie ZP, Xie GC, Sun XM, Pang LL, Xu JG, Lipkin WI, Duan ZJ. A novel hepatovirus identified in wild woodchuck Marmota himalayana. Scientific Reports. 6:22361. doi: 10.1038/srep22361.

9. Yu JM, Ao YY, Liu N, Li LL, Duan ZJ. Salivirus in Children and Its Association with Childhood Acute Gastroenteritis: A Paired Case-Control Study. PLoS One. 10(7): e0130977. 

8.Yu JM, Zhao G, AoYY, LI LL, Wang D, Duan ZJ. Complete Genome Sequence of a Novel Human Papillomavirus Identified by Metagenomic Analysis from a Child with Diarrhea in China. Archives Virology.160(2):549-52. 

7. Yu JM, Li JS, Ao YY, Duan ZJ. Detection of novel viruses in porcine fecal samples from China.Virolology Journal. 2013 Jan 30;10:39. 

6. Yu JM, Chen QQ, Hao YX, Yu T, Zeng SZ, WU XB，Zhang B, Duan ZJ. Identification of Human Bocaviruses in the Cerebrospinal Fluid of Children hospitalized with Encephalitis in China. Journal of Clinical Virology.  2013 Aug;57(4):374-7. doi: 10.1016/j.jcv.2013.04.008. Epub 2013 May 23. 

5. Yu JM, Li XY, AoYY, LI LL, Liu N, LI JS, Duan ZJ. Identification of a novel Parechovirus-like virus in healthy piglets and seroepidemiological evidence of its presence in humans. PLoS One.2013 Aug 6;8(8). Print 2013. 

4. Yu JM, Ao YY, Zhao G, Li LL, Wang D, Duan ZJ. Identification of a Novel Strain of Human Papillomavirus from Children with Diarrhea in China. Genome Announcement. 2013 Oct 3;1(5). doi:pii: e00761-13. 10.1128/genomeA.00761-13. 

3. Yu JM, Xu ZQ, Li BW, Zhang Q, Cui SX, Jin M, Duan ZJ. Analysis and characterization of the complete genome of a member of a new species of kobuvirus associated with swine. Archives Virology. 2011 May; 156(5):747-51. 

2. Yu JM, Jin M, Zhang Q, Li HY, Li DD, Xu ZQ, Li JS, Liu N, Duan ZJ. Candidate porcine Kobuvirus, China. Emerging Infectious Diseases. 2009 May; 15(5):823-5. 

1. Yu JM, Li DD, Xu ZQ, Cheng WX, Zhang Q, Li HY, Cui SX, Miao-Jin, Yang SH, Fang ZY, Duan ZJ. Human bocavirus infection in children hospitalized with acute gastroenteritis in China. Journal of Clinical Virology. 2008 Jul; 42(3):280-5. 


专著/译著

专利

1、付远辉；何金生；郑妍鹏；彭向雷；虞结梅；一种RSV融合前F蛋白、表达质粒、细胞株和RSV疫苗组合物，专利号：ZL 202111536309.9，授权公告日：2024年05月03日

2、付远辉；何金生；黄蕾；虞结梅；彭向雷；郑妍鹏；两种表达水痘-带状疱疹病毒的 gE 蛋白的重组腺病毒及应用，专利号：ZL 202111536306.5，授权公告日：2023年10月31日

3、段招军; 李利利; 虞结梅; 庞立丽; 一种新型甲肝病毒动物模型的构建方法及其 应用, 2016-2-24, 中国, CN201510836374.1

4 、段招军; 虞结梅; 李利利; 敖元云; 一种新型甲型肝炎病毒株及其应用, 2016-2- 24, 中国, CN201510836360.X

软件著作权

获奖与荣誉

社会兼职

中国疫苗行业协会疫苗学教育专委会委员；国家自然科学基金通讯评审专家；多种国内国际期刊审稿专家。